Neuropsychopharmacology - Figure 1 for article: The 5-HT2C Receptor Agonist Ro60-0175 Reduces Cocaine Self-Administration and Reinstatement Induced by the Stressor Yohimbine, and Contextual Cues

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The 5-HT_2C Receptor Agonist Ro60-0175 Reduces Cocaine Self-Administration and Reinstatement Induced by the Stressor Yohimbine, and Contextual Cues

Paul J Fletcher, Zoë Rizos, Judy Sinyard, Maria Tampakeras and Guy A Higgins

Figure 1.

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The effects of daily treatment with 1 mg/kg Ro60-0175 (n=8) or saline (n=8) on the number of cocaine infusions earned on a progressive ratio schedule of reinforcement. Symbols represent the mean plusminus SEM number of infusions for the two groups of animals. Data points at B1–B3 show the average number of cocaine infusions during the last 3 days of the baseline phase. ^** p<0.01 compared to saline on all days.

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FIGURE 1

The 5-HT2C Receptor Agonist Ro60-0175 Reduces Cocaine Self-Administration and Reinstatement Induced by the Stressor Yohimbine, and Contextual Cues

Figure 1.

The 5-HT_2C Receptor Agonist Ro60-0175 Reduces Cocaine Self-Administration and Reinstatement Induced by the Stressor Yohimbine, and Contextual Cues