Neuropsychopharmacology

TABLE 1

FROM:

Bupropion for the Treatment of Methamphetamine Dependence

Ahmed M Elkashef, Richard A Rawson, Ann L Anderson, Shou-Hua Li, Tyson Holmes, Edwina V Smith, Nora Chiang, Roberta Kahn, Frank Vocci, Walter Ling, Valerie J Pearce, Michael McCann, Jan Campbell, Charles Gorodetzky, William Haning, Barry Carlton, Joseph Mawhinney and Dennis Weis

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Table 1. Baseline Characteristics of Randomized Participants for the Bupropion-Methamphetamine Study

  Bupropion Placebo  
  N=79 N=72 p-values
Age (years)36.2(9.2)a 35.7(8.4)0.72
      
Gender     0.33
 Male50(63%)51(71%) 
 Female29(37%)21(29%) 
 
Race     0.93
 White, not Hispanic59(75%)53(74%) 
 Hispanic or Latino5(6%)5(7%) 
 African American or Black2(3%)2(3%) 
 Asian or Pacific Islander11(14%)10(14%) 
 American Indian or Alaska1(1%)0(0%) 
 Other1(1%)2(3%) 
      
Years of education12.6(1.9)a 12.4(1.7)0.48
      
Days of methamphetamine use in last 30 days     0.66
 less than or equal to1836(46%)35(49%) 
 >1843(54%)37(51%) 
      
Lifetime years of methamphetamine use10.42(7.59)a 9.97(6.10)0.69
      
Route of lifetime methamphetamine use     0.66
 Nasal15(19%)10(14%) 
 Smoking49(62%)49(68%) 
 Injection15(19%)13(18%) 
      
Baseline period urine methamphetamine screens (% positive) 82.9% 80.3% 
      
Depression (HAM-D score)     0.78
 less than or equal to1264(81%)57(79%) 
 >1215(19%)15(21%) 
      
Adult ADHD     0.03
 No73(92%)58(81%) 
 Yes6(8%)14(19%) 

a Standard deviation.

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