Neuropsychopharmacology

FIGURE 5

FROM:

Adolescent Cannabis Exposure Alters Opiate Intake and Opioid Limbic Neuronal Populations in Adult Rats

Maria Ellgren, Sabrina M Spano and Yasmin L Hurd

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Figure 5.

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Heroin-seeking behavior (responding on the active lever in the absence of expected drug delivery; no cue light presentation) in THC- (n=5) or vehicle- (n=5) exposed rats with and without acute Rimonabant pretreatment prior to the self-administration session. * p<0.05; **** p<0.0001 as compared to baseline. +++ p<0.001 vs drug-seeking paradigm without Rimonabant pretreatment.

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