Neuropsychopharmacology

TABLE 2

FROM:

Dopamine Transporter Gene (DAT1) Associated with Appetite Suppression to Methylphenidate in a Case–Control Study of Binge Eating Disorder

Caroline Davis, Robert D Levitan, Allan S Kaplan, Jacqueline Carter, Caroline Reid, Claire Curtis, Karen Patte and James L Kennedy

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Table 2. Allele and Genotype Frequencies for DAT1 VNTR Polymorphism for 32 BED and 46 Healthy Control Subjects with Common Genotypes

  Allele Genotype
  9-Repeat 10-Repeat 9/9 9/10 10/10
BED17 (26.8%)47 (73.2%)1 (3.1%)15 (46.9)16 (50%)
Control21 (23.9%)71 (76.1%)3 (6.5%)15 (32.6%)28 (60.9%)

 Five additional subjects not included in the analyses each had a rare allele. One subject had the 12-repeat and two had the 11-repeat, all heterozygous with the 9-repeat allele. Two others had the 6/10 combination. Allele frequencies of the remaining subjects are similar to those reported in other studies (eg Lott et al, 2005). chi 2 analysis indicated no significant differences in genotype frequencies between BED and control subjects possessing the common alleles (chi 2=1.82, p=0.403).

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