TABLE 2
FROM:
Dopamine Transporter Gene (DAT1) Associated with Appetite Suppression to Methylphenidate in a Case–Control Study of Binge Eating Disorder
Caroline Davis, Robert D Levitan, Allan S Kaplan, Jacqueline Carter, Caroline Reid, Claire Curtis, Karen Patte and James L Kennedy
BACK TO ARTICLETable 2. Allele and Genotype Frequencies for DAT1 VNTR Polymorphism for 32 BED and 46 Healthy Control Subjects with Common Genotypes
| Allele | Genotype | ||||
|---|---|---|---|---|---|
| 9-Repeat | 10-Repeat | 9/9 | 9/10 | 10/10 | |
| BED | 17 (26.8%) | 47 (73.2%) | 1 (3.1%) | 15 (46.9) | 16 (50%) |
| Control | 21 (23.9%) | 71 (76.1%) | 3 (6.5%) | 15 (32.6%) | 28 (60.9%) |
Five additional subjects not included in the analyses each had a rare allele. One subject had the 12-repeat and two had the 11-repeat, all heterozygous with the 9-repeat allele. Two others had the 6/10 combination. Allele frequencies of the remaining subjects are similar to those reported in other studies (eg Lott et al, 2005).
2 analysis indicated no significant differences in genotype frequencies between BED and control subjects possessing the common alleles (
2=1.82, p=0.403).
