Neuropsychopharmacology

FIGURE 2

FROM:

Regional Heterogeneity for the Intracranial Self-Administration of Ethanol and Acetaldehyde within the Ventral Tegmental Area of Alcohol-Preferring (P) Rats: Involvement of Dopamine and Serotonin

Zachary A Rodd, Richard L Bell, Ying Zhang, James M Murphy, Avram Goldstein, Alejandro Zaffaroni, Ting-Kai Li and William J McBride

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Figure 2.

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Average infusions across the four acquisition sessions for the self-administration of (a) 0–300 mg% ethanol (EtOH) into the posterior and anterior VTA (top panels; n=6/dose for each subregion), and (b) 0–60 muM acetaldehyde (ACD) into the posterior and anterior VTA (bottom panels; n=6/dose for each subregion). *Indicates that number of infusions is significantly (p<0.05) higher than infusions of (a) 0 and 50 mg% EtOH, or (b) 0, 3, 180 and 360 muM ACD. #Indicates that number of infusions is significantly (p<0.05) higher than (a) 0, 50 and 300 mg% EtOH, or (b) 0, 3, 90, 180 and 360 muM ACD. Data are the meansplusminusSEM.

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