Neuropsychopharmacology

FIGURE 4

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Blockade by the Cannabinoid CB1 Receptor Antagonist, Rimonabant (SR141716), of the Potentiation by Quinelorane of Food-Primed Reinstatement of Food-Seeking Behavior

Christine Duarte, Richard Alonso, Nicole Bichet, Caroline Cohen, Philippe Soubrié and Marie-Hélène Thiébot

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Figure 4.

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Effect of rimonabant on Fos expression in CB1+/+ and CB1-/- mice. Animals were given either vehicle (Veh) or rimonabant (SR, 10 mg/kg, i.p.), 2 h before being killed. Data are the number (mean+SEM) of Fos-positive cells counted within the indicated brain region (n=7 in vehicle- and n=6 in rimonabant-injected mice of each genotype). ** p<0.01 rimonabant vs vehicle, in mice of the same genotype. * p<0.05 vs vehicle-treated CB1+/+ mice. †† p<0.01 vs rimonabant-treated CB1+/+ mice (Dunn's t-test after ANOVA).

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