Clinical Research

Neuropsychopharmacology (2003) 28, 359–370. doi:10.1038/sj.npp.1300030

A Self-Administered Questionnaire to Measure Dependence on Cigarettes: The Cigarette Dependence Scale

Jean-François Etter1, Jacques Le Houezec2 and Thomas V Perneger1,3

  1. 1Institute of Social and Preventive Medicine, University of Geneva, Switzerland
  2. 2Pharmacia R&D Consumer Healthcare, Helsingborg, Sweden
  3. 3Quality of Care Unit, Geneva University Hospitals, Switzerland

Correspondence: J-F Etter, Institute of Social and Preventive Medicine, University of Geneva, CMU, Case Postale, CH-1211 Geneva 4, Switzerland. Tel: +41 22 702 59 19; Fax: +41 22 702 59 12; E-mail: Jean-Francois.Etter@imsp.unige.ch. Internet: www.stop-tabac.ch

Received 20 February 2002; Revised 10 June 2002; Accepted 10 July 2002.

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Abstract

A valid measure of dependence on cigarettes is a useful tool for clinicians and researchers. The aim of this study was to develop a new, self-administered measure of cigarette dependence, and to assess its validity. The content of the instrument was generated in qualitative surveys. A long version (114 items) was tested on the internet in 3009 smokers. Subsamples provided retest data after 18 days (n=578), follow-up data after 45 days (n=990) and saliva cotinine (n=105). The study resulted in a 12-item scale labelled the Cigarette Dependence Scale (CDS-12), and in a 5-item version of this scale (CDS-5). Except for tolerance, CDS-12 covers the main components of DSM-IV and ICD-10 definitions of dependence: compulsion, withdrawal symptoms, loss of control, time allocation, neglect of other activities, and persistence despite harm. CDS-5 has similar measurement properties but less comprehensive content. Both scales had a high test–retest reliability (rgreater than or equal to0.83), and a high internal consistency (Cronbach's alphagreater than or equal to0.84). CDS-12 scores were higher in daily smokers than in occasional smokers (+1.3SD units), and were associated with the strength of the urge to smoke during the last quit attempt (R2greater than or equal to0.25), and with saliva cotinine (R2greater than or equal to0.17). CDS-12 and CDS-5 scores decreased in daily smokers who switched to occasional smoking at 18-day retest. Dependence scores did not predict smoking abstinence at follow-up. In conclusion, CDS-12 and CDS-5 are reliable measures of cigarette dependence which fulfill several criteria of content validity and construct validity and are sensitive to change over time.

Keywords:

tobacco use disorder, nicotine dependence, smoking, validation studies, epidemiologic measurements, internet

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