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The development of sophisticated devices to monitor, and eventually interfere with, essential cellular processes is an ongoing challenge. Now, Jos A. Plaza and colleagues have fabricated silicon chips that are small enough to be internalized inside cells and detect intracellular pressure changes. These devices can be considered the first step towards achieving a broad range of intracellular nanochips. A pseudocoloured scanning microscopy image (on the cover) shows a HeLa cell interacting with a silicon chip pressure sensor.
The theoretical work done by Lyndon Hicks and Mildred Dresselhaus 20 years ago on the effect of reduced dimensionality on thermoelectric efficiency has had deep implications beyond the initial expectations.
Nanobots have in the past been a fixture of science fiction writing and illustration, and such ideas are now also appearing in scientific research. But, as Chris Toumey explains, practical nanobots are different from their science fiction counterparts.
The combination of a plasmonic nanoantenna and a nanoaperture has merged fluorescence enhancement and spatial confinement to enable single-molecule detection at biologically relevant concentrations.
A very sensitive photodector based on molybdenum disulphide with potential for integrated optoelectronic circuits, light sensing, biomedical imaging, video recording or spectroscopy is now demonstrated.
Two-dimensional arrays of plasmonic nanoparticles coupled with a gain medium can behave as a surface-emitting laser with near-zero group velocity and picosecond dynamics.
A plasmonic nanoantenna enables a thousand fold-enhanced fluorescence brightness allowing single-molecule analysis to be carried out in a zeptolitre volume at physiological concentrations.
The influence of magnetic fields on the current-driven motion of domain walls in nanowires with perpendicular anisotropy shows that two spin–orbit-derived mechanisms are responsible for their motion.