Treatment of mammalian cells with dilute silicic acid followed by heating forms silica replicas of the cell template, offering a way to preserve cell specimens and generate biocomposites for various applications.
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References
Fratzl, P. & Weiner, S. Adv. Mater. 22, 4547–4550 (2010).
Khripin, C. Y., Pristinski, D., Dunphy, D. R., Brinker, C. J. & Kaehr, B. ACS Nano 5, 1401–1409 (2011).
Kaehr, B. et al. Proc. Natl Acad. Sci. USA 109, 17336–17341 (2012).
Huo, Q. S. et al. Nature 368, 317–321 (1994).
Sun, T. & Ying, J. Y. Nature 389, 704–706 (1997).
Zhao, D. et al. Science 279, 548–552 (1998).
Kresge, C. T., Leonowicz, M. E., Roth, W. J., Vartuli, J. C. & Beck, J. S. Nature 359, 710–712 (1992).
Tanev, P. T. & Pinnavaia, T. J. Science 267, 865–867 (1995).
Antonelli, D. M. & Ying, J. Y. Angew. Chem. Int. Ed. Engl. 34, 2014–2017 (1995).
Gilbert, T. W., Sellaro, T. L. & Badylak, S. F. Biomaterials 27, 3675–3683 (2006).
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Ying, J. Cells made of silica. Nature Nanotech 7, 777–778 (2012). https://doi.org/10.1038/nnano.2012.215
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DOI: https://doi.org/10.1038/nnano.2012.215
