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The lateral feature resolution in conventional far-field optical lithography is diffraction-limited, and although methods have been developed to beat this limit, they can be difficult to implement and/or are limited in the range of patterns they can produce. Chad Mirkin and co-workers have now shown that a combination of nearfield scanning optical microscopy and polymer-pen lithography — a technique based on scanning probe microscopy — can overcome these problems. In this new approach, which is called beam-pen lithography, light is passed through nanoscale apertures at the end of each tip in a two-dimensional array of pyramid-shaped 'pens', allowing large areas to be patterned with high throughput. The cover shows an optical microscopy image of a representative region of ~15,000 duplicate photoresist patterns of a Chicago skyline. The entire cover image is about 300 micrometres across.
All scientists should find the time to understand the software packages that they use to collect, analyse and display their data, and share this knowledge with new researchers.
An array of polymer tips that can channel light to an underlying substrate can be used to generate intricate nanostructures with high throughput and over large areas.
Complex artificial networks of genes have been designed that can sense a number of input signals in a user-defined logic to produce predictable output behaviours in mammalian cells.
A method that characterizes the adsorption of a set of small molecules on different nanoparticles may offer a way to predict how proteins interact with them.
A technique based on scanning probe microscopy, which uses a two-dimensional array of nanoscopic apertures fabricated at the end of polymer tips to channel light to an underlying substrate, can be used to generate arbitrary patterns with both sub-diffraction limit and larger feature sizes over large areas.
Micrometre-thick supercapacitors made from onion-like carbon nanoparticles exhibit orders of magnitude higher capacitance and energy density compared with electrolytic capacitors, and much higher charging/discharging rates than conventional supercapacitors.
A significant enhancement in the conductance of a graphene nanoribbon field-effect transistor is observed when a perpendicular magnetic field is applied.
Two-step bioorthogonal chemistry increases nanoparticle binding for more sensitive cell detection compared with standard techniques, including the biotin–avidin system.
Multiple-transcription-factor proteins are used to build complex logic circuits inside mammalian cells, offering a platform for intelligent therapeutics that interact with biological environments.
By quantifying the competitive adsorption of chemicals and biomolecules onto nanoparticles, an index is developed for characterizing nanomaterials in biological systems, offering a way to create models for predicting the safety of nanomaterials.