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Volume 5 Issue 9, September 2010

The lateral feature resolution in conventional far-field optical lithography is diffraction-limited, and although methods have been developed to beat this limit, they can be difficult to implement and/or are limited in the range of patterns they can produce. Chad Mirkin and co-workers have now shown that a combination of nearfield scanning optical microscopy and polymer-pen lithography — a technique based on scanning probe microscopy — can overcome these problems. In this new approach, which is called beam-pen lithography, light is passed through nanoscale apertures at the end of each tip in a two-dimensional array of pyramid-shaped 'pens', allowing large areas to be patterned with high throughput. The cover shows an optical microscopy image of a representative region of ~15,000 duplicate photoresist patterns of a Chicago skyline. The entire cover image is about 300 micrometres across.

Letter p637; News & Views p629

Editorial

  • All scientists should find the time to understand the software packages that they use to collect, analyse and display their data, and share this knowledge with new researchers.

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News & Views

  • An array of polymer tips that can channel light to an underlying substrate can be used to generate intricate nanostructures with high throughput and over large areas.

    • Aaron Hernandez-Santana
    • Duncan Graham
    News & Views
  • Targeting magnetic nanoparticles to tumours then applying an alternating magnetic field can improve the contrast for infrared thermal imaging.

    • John B. Weaver
    News & Views
  • Complex artificial networks of genes have been designed that can sense a number of input signals in a user-defined logic to produce predictable output behaviours in mammalian cells.

    • Guilhem Chalancon
    • M. Madan Babu
    News & Views
  • A method that characterizes the adsorption of a set of small molecules on different nanoparticles may offer a way to predict how proteins interact with them.

    • Jerzy Leszczynski
    News & Views
  • An RNA nanocube can self-assemble isothermally during in vitro transcription.

    • Michael Famulok
    • Damian Ackermann
    News & Views
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