Article abstract


Nature Nanotechnology 5, 61 - 66 (2010)
Published online: 8 November 2009 | doi:10.1038/nnano.2009.311

Subject Categories: Carbon nanotubes and fullerenes | Molecular self-assembly

Self-assembly of carbon nanotubes into two-dimensional geometries using DNA origami templates

Hareem T. Maune1,2, Si-ping Han1,2, Robert D. Barish1,2, Marc Bockrath1, William A. Goddard III1, Paul W. K. Rothemund1 & Erik Winfree1


A central challenge in nanotechnology is the parallel fabrication of complex geometries for nanodevices. Here we report a general method for arranging single-walled carbon nanotubes in two dimensions using DNA origami—a technique in which a long single strand of DNA is folded into a predetermined shape. We synthesize rectangular origami templates (~75 nm × 95 nm) that display two lines of single-stranded DNA ‘hooks’ in a cross pattern with ~6 nm resolution. The perpendicular lines of hooks serve as sequence-specific binding sites for two types of nanotubes, each functionalized non-covalently with a distinct DNA linker molecule. The hook-binding domain of each linker is protected to ensure efficient hybridization. When origami templates and DNA-functionalized nanotubes are mixed, strand displacement-mediated deprotection and binding aligns the nanotubes into cross-junctions. Of several cross-junctions synthesized by this method, one demonstrated stable field-effect transistor-like behaviour. In such organizations of electronic components, DNA origami serves as a programmable nanobreadboard; thus, DNA origami may allow the rapid prototyping of complex nanotube-based structures.

Top
  1. California Institute of Technology, Pasadena, California 91125, USA
  2. These authors contributed equally to this work

Correspondence to: Si-ping Han1,2 e-mail: si-ping@wag.caltech.edu



MORE ARTICLES LIKE THIS

These links to content published by NPG are automatically generated.

REVIEWS

Applications of dip-pen nanolithography

Nature Nanotechnology Review (01 Mar 2007)

NEWS AND VIEWS

DNA nanotechnology Geometric sorting boards

Nature Nanotechnology News and Views (01 Sep 2009)

Conducting polymers Fine printing

Nature Materials News and Views (01 Mar 2004)