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Nanoelectromechanical systems

Mass spec goes nanomechanical

A new approach to mass spectrometry based on nanoelectromechanical systems removes the need to ionize molecules before their mass can be determined.

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Figure 1: The resonant frequency of a nanoscale bridge (grey) is reduced when molecules (orange) land on it, with the frequency change depending on the mass of the molecule and where it lands on the bridge.

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Boisen, A. Mass spec goes nanomechanical. Nature Nanotech 4, 404–405 (2009). https://doi.org/10.1038/nnano.2009.169

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