Article abstract
Nature Nanotechnology 3, 434 - 439 (2008)
Published online: 29 June 2008 | doi:10.1038/nnano.2008.174
Subject Categories: Carbon nanotubes and fullerenes | Nanomedicine | Nanometrology and instrumentation | Nanosensors and other devices | Surface patterning and imaging
Carbon nanotube coating improves neuronal recordings
Edward W. Keefer1, Barry R. Botterman2, Mario I. Romero1,3, Andrew F. Rossi4 & Guenter W. Gross5
Abstract
Implanting electrical devices in the nervous system to treat neural diseases is becoming very common. The success of these brain–machine interfaces depends on the electrodes that come into contact with the neural tissue. Here we show that conventional tungsten and stainless steel wire electrodes can be coated with carbon nanotubes using electrochemical techniques under ambient conditions. The carbon nanotube coating enhanced both recording and electrical stimulation of neurons in culture, rats and monkeys by decreasing the electrode impedance and increasing charge transfer. Carbon nanotube-coated electrodes are expected to improve current electrophysiological techniques and to facilitate the development of long-lasting brain–machine interface devices.
- UTSW Medical School, Department of Plastic Surgery, Dallas, Texas 75390, USA
- UTSW Medical School, Department of Cell Biology, Dallas, Texas 75390, USA
- Texas Scottish Rite Hospital for Children, Dallas, Texas 75219, USA
- Vanderbilt University, Department of Psychology, Nashville, Tennessee 37203, USA
- University of North Texas, Department of Biology, Denton, Texas 76203, USA
Correspondence to: Edward W. Keefer1 e-mail: edward.keefer@utsouthwestern.edu
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