Table of contents



Correction p283


See also: Editorial



Re-inventing print p283


Emerging 2D-material-based inks could find applications in next-generation printed electronics.



Playing and laughing among the molecules pp284 - 285

Chris Toumey


Chris Toumey reflects on the fun, and not only, provided by nanotechnology in the digital world, as illustrated by Colin Milburn in Mondo Nano.


Research Highlights

Our choice from the recent literature p286

Alberto Moscatelli, Giacomo Prando, Victoria Richards & Wenjie Sun



News and Views

Two-dimensional materials: Printing functional atomic layers pp287 - 288

Deji Akinwande


A new approach for the formulation of 2D-nanomaterial dispersions in water with additives, which allows layers to be printed on top of one another with distinctive interfaces, can enable inkjet-printed complex circuits.

See also: Article by McManus et al.

Nanomedicine: Evolution of the nanoparticle corona pp288 - 290

Marilena Hadjidemetriou & Kostas Kostarelos


Understanding how complement proteins bind to nanoparticles and participate in their surface 'corona' can provide further insight into the relevance of the protein corona concept in medicine.

See also: Article by Chen et al.

Nanosystem: Programmed communication pp291 - 292

Kristiana Kandere-Grzybowska & Bartosz A. Grzybowski


Autocatalytic nanoparticles activated and deactivated by DNA 'programs' can trigger through-space molecular communication and give rise to collective particle behaviours.

See also: Article by Gines et al.

Graphene fragments: When 1 + 1 is odd pp292 - 293

Manuel Melle-Franco


Triangulene, an elusive open-shell magnetic molecule, is synthesized and characterized by electron microscopy.

See also: Letter by Pavliček et al.



Imaging modes of atomic force microscopy for application in molecular and cell biology pp295 - 307

Yves F. Dufrêne, Toshio Ando, Ricardo Garcia, David Alsteens, David Martinez-Martin, Andreas Engel, Christoph Gerber & Daniel J. Müller


This Review Article examines the principles, advantages and limitations of emerging bioimaging modes of atomic force microscopy, including multiparametric, molecular recognition, multifrequency and high-speed imaging.



Synthesis and characterization of triangulene pp308 - 311

Niko Pavliček, Anish Mistry, Zsolt Majzik, Nikolaj Moll, Gerhard Meyer, David J. Fox & Leo Gross


A combined scanning tunnelling and atomic force microscopy approach is used to generate and characterize triangulene on various surfaces.

See also: News and Views by Melle-Franco

Self-assembling DNA nanotubes to connect molecular landmarks pp312 - 316

Abdul M. Mohammed, Petr Šulc, John Zenk & Rebecca Schulman


DNA nanotubes can grow to connect two molecules attached to surfaces with arbitrary micron-scale separation.

Water-evaporation-induced electricity with nanostructured carbon materials pp317 - 321

Guobin Xue, Ying Xu, Tianpeng Ding, Jia Li, Jun Yin, Wenwen Fei, Yuanzhi Cao, Jin Yu, Longyan Yuan, Li Gong, Jian Chen, Shaozhi Deng, Jun Zhou & Wanlin Guo


Water evaporation from the surface of cheap carbon-black materials can be used to generate sustained voltages of up to 1V under ambient conditions.

Fluorescent nanodiamond tracking reveals intraneuronal transport abnormalities induced by brain-disease-related genetic risk factors pp322 - 328

Simon Haziza, Nitin Mohan, Yann Loe-Mie, Aude-Marie Lepagnol-Bestel, Sophie Massou, Marie-Pierre Adam, Xuan Loc Le, Julia Viard, Christine Plancon, Rachel Daudin, Pascale Koebel, Emilie Dorard, Christiane Rose, Feng-Jen Hsieh, Chih-Che Wu, Brigitte Potier, Yann Herault, Carlo Sala, Aiden Corvin, Bernadette Allinquant, Huan-Cheng Chang, François Treussart & Michel Simonneau


Tracking fluorescent nanodiamond inside branches of neurons is a sensitive method to measure the changes in intraneuronal transport due to genetic risk factors associated with brain diseases.



Opto-valleytronic imaging of atomically thin semiconductors pp329 - 334

Andre Neumann, Jessica Lindlau, Léo Colombier, Manuel Nutz, Sina Najmaei, Jun Lou, Aditya D. Mohite, Hisato Yamaguchi & Alexander Högele


Monolayer semiconductors reveal their crystal quality and valleytronic properties in two-dimensional polarimetric imaging.

Targeted intracellular voltage recordings from dendritic spines using quantum-dot-coated nanopipettes pp335 - 342

Krishna Jayant, Jan J. Hirtz, Ilan Jen-La Plante, David M. Tsai, Wieteke D. A. M. De Boer, Alexa Semonche, Darcy S. Peterka, Jonathan S. Owen, Ozgur Sahin, Kenneth L. Shepard & Rafael Yuste


Dendritic spine voltages are recorded directly using quantum-dot-coated nanopipette electrodes under two-photon visualization, demonstrating that spines receive large synaptic potentials.

Water-based and biocompatible 2D crystal inks for all-inkjet-printed heterostructures pp343 - 350

Daryl McManus, Sandra Vranic, Freddie Withers, Veronica Sanchez-Romaguera, Massimo Macucci, Huafeng Yang, Roberto Sorrentino, Khaled Parvez, Seok-Kyun Son, Giuseppe Iannaccone, Kostas Kostarelos, Gianluca Fiori & Cinzia Casiraghi


Device fabrication can be realized via inkjet printing of water-based 2D crystals.

See also: News and Views by Akinwande

Microscopic agents programmed by DNA circuits pp351 - 359

G. Gines, A. S. Zadorin, J.-C. Galas, T. Fujii, A. Estevez-Torres & Y. Rondelez


Individual particles can be programmed to chemically communicate with their neighbours, giving rise to collective behaviours such as dynamic travelling fronts and spatial pattern creation.

See also: News and Views by Kandere-Grzybowska & Grzybowski

Real-time shape approximation and fingerprinting of single proteins using a nanopore pp360 - 367

Erik C. Yusko, Brandon R. Bruhn, Olivia M. Eggenberger, Jared Houghtaling, Ryan C. Rollings, Nathan C. Walsh, Santoshi Nandivada, Mariya Pindrus, Adam R. Hall, David Sept, Jiali Li, Devendra S. Kalonia & Michael Mayer


The zeptolitre sensing volume of bilayer-coated solid-state nanopores can be used to determine the approximate shape, volume, charge, rotational diffusion coefficient, and dipole moment of individual proteins.

Single-molecule detection of protein efflux from microorganisms using fluorescent single-walled carbon nanotube sensor arrays pp368 - 377

Markita Patricia Landry, Hiroki Ando, Allen Y. Chen, Jicong Cao, Vishal Isaac Kottadiel, Linda Chio, Darwin Yang, Juyao Dong, Timothy K. Lu & Michael S. Strano


Nanosensor arrays based on single-walled carbon nanotubes can detect protein efflux from single, isolated microorganisms in real time, allowing the dynamics of genetic transfection and influence of reproduction to be measured.

Magnesium silicide nanoparticles as a deoxygenation agent for cancer starvation therapy pp378 - 386

Chen Zhang, Dalong Ni, Yanyan Liu, Heliang Yao, Wenbo Bu & Jianlin Shi


Magnesium silicide nanoparticles can scavenge oxygen in the acidic tumour microenvironment and starve tumours by blocking oxygen and nutrient supply, offering a new avenue for cancer-starvation therapy.

Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo pp387 - 393

Fangfang Chen, Guankui Wang, James I. Griffin, Barbara Brenneman, Nirmal K. Banda, V. Michael Holers, Donald S. Backos, LinPing Wu, Seyed Moein Moghimi & Dmitri Simberg


Immune proteins bind to protein corona on core-shell nanoparticles and undergo dynamic exchange in vivo.

See also: News and Views by Hadjidemetriou & Kostarelos


In The Classroom

In pursuit of waves p394

Nader Engheta


Passion for science and technology can be a powerful motivator to overcome hurdles, as Nader Engheta explains, recounting his own experience as an immigrant.


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