About the cover

November 2015 Volume 10 No 11

Unlike DNA, the use of proteins as building blocks for engineering biological devices has remained largely unexplored. Philip Dannhauser and colleagues have now formed regular two-dimensional lattices of clathrin, a three-legged protein complex, on a variety of solid supports. The lattices can be dehydrated and rehydrated without the loss of function, and can be stored for months, offering potential applications in biosensing. The cover shows an electron micrograph of an irregular aluminium surface coated with regular clathrin lattices (magnification: 165,000×). The surface was prepared by critical point drying and subsequent shadowing with platinum and carbon.

Letter p954

IMAGE: PHILIP DANNHAUSER (MEDICAL SCHOOL HANNOVER)

COVER DESIGN: KAREN MOORE

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