Review Articles in 2020

Recent advances in genome sequencing have started to reveal an increasing diversity and distribution of archaeal genomes across multiple ecosystems. In this Review, Baker and colleagues discuss how these genomes elucidate the metabolic capabilities of the Archaea and their ecological roles, while also expanding our view of the tree of life and of eukaryogenesis.

Flaviviruses, a group of vector-borne RNA viruses that includes dengue virus, West Nile virus, Zika virus and several lesser-known species, often emerge in human populations and cause epidemics. Here, Pierson and Diamond review the basic biology of these viruses, their life cycles, the diseases they cause and available therapeutic options. They also discuss the global distribution of flaviviruses, with a focus on lesser-known species that have the potential to emerge more broadly in human populations.