Method of the year:
Next-generation sequencing
Nature Methods
Next-generation sequencing has been selected as the Method of the Year 2007 by Nature Methods and a special feature will appear online this week in the journal.
Next-generation sequencing consists of several methods, which have permitted a drastic reduction in sequencing cost and a dramatic increase in throughput. Although they started to appear on the market in 2005, in 2007 they really came into their own, with several impressive and successful applications. The broad range of uses for next-generation sequencing and the fact that novel applications beyond the original purpose are also in use have earned this development the title of Method of the Year.
The feature recounts the development of these methods and the major events in 2007 that contributed to firmly establish them in the community. A Commentary by Stephan Schuster and another by Barbara Wold and Rick Myers showcase the broad range of applications. Stephan Schuster argues that next-generation sequencing "has brought the field of genomics back into the laboratories of single investigators or small academic consortia".
In addition to celebrating the Method of the Year 2007 the special feature contains a shortlist of Methods to Watch in the years to come.
Authors contact for the two Commentaries:
Stephan Schuster (Pennsylvania State University, Pennsylvania, USA)
Tel: +1 814 863 9278; E-mail: scs@bx.psu.edu
Barbara Wold (California Institute of Technology, Pasadena, California, USA)
Tel: +1 626.395.4916; E-mail: bwold@caltech.edu
Richard M. Myers (Stanford University School of Medicine, Stanford, California, USA)
Tel: +1 650 725 9687; E-mail: myers@shgc.stanford.edu
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