Nature Methods
Nature Methods offers a unique interdisciplinary forum for the publication of novel methods. Nature Methods focuses on the life sciences, combining practical, technique-driven subject matter with rigorous peer-review standards to ensure that readers are consistently presented with only the most valuable and highest quality methodological research. The journal offers its readers primary research papers as well as an array of opinions, reviews and short journalistic pieces to provide busy researchers with a broad, yet easily absorbed perspective of important methodological developments in the life sciences.
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Nature Methods
© 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.
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Nature Methods
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https://www.nature.com/articles/s41592-024-02215-8
Nature Methods, Published online: 15 March 2024; doi:10.1038/s41592-024-02215-8A benchmark study compares 13 spatial clustering methods on spatial transcriptomics data.]]>
Zhiyuan YuanFangyuan ZhaoSenlin LinYu ZhaoJianhua YaoYan CuiXiao-Yong ZhangYi Zhao
doi:10.1038/s41592-024-02215-8
Nature Methods, Published online: 2024-03-15; | doi:10.1038/s41592-024-02215-8
2024-03-15
Nature Methods
10.1038/s41592-024-02215-8
https://www.nature.com/articles/s41592-024-02215-8
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https://www.nature.com/articles/s41592-024-02223-8
Nature Methods, Published online: 14 March 2024; doi:10.1038/s41592-024-02223-8The exceptionally photostable green fluorescent protein StayGold has been monomerized in different laboratories, which has generated three unique monomeric variants that will enable new imaging applications.]]>
Joachim GoedhartTheodorus W. J. Gadella Jr
doi:10.1038/s41592-024-02223-8
Nature Methods, Published online: 2024-03-14; | doi:10.1038/s41592-024-02223-8
2024-03-14
Nature Methods
10.1038/s41592-024-02223-8
https://www.nature.com/articles/s41592-024-02223-8
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https://www.nature.com/articles/s41592-024-02224-7
Nature Methods, Published online: 14 March 2024; doi:10.1038/s41592-024-02224-7New condenser aperture designs form square or rectangular beams that match the camera dimensions, which efficiently expands the data acquisition area in cryogenic electron microscopy.]]>
Xiaowei Zhao
doi:10.1038/s41592-024-02224-7
Nature Methods, Published online: 2024-03-14; | doi:10.1038/s41592-024-02224-7
2024-03-14
Nature Methods
10.1038/s41592-024-02224-7
https://www.nature.com/articles/s41592-024-02224-7
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https://www.nature.com/articles/s41592-024-02209-6
Nature Methods, Published online: 13 March 2024; doi:10.1038/s41592-024-02209-6MINSTED quantifies tiny movements of individual biomolecules with high spatiotemporal precision to successfully resolve the steps of the molecular motor protein kinesin-1 labeled with a single fluorophore as it switches protofilaments.]]>
Lukas ScheidererHenrik von der EmdeMira HesselinkMichael WeberStefan W. Hell
doi:10.1038/s41592-024-02209-6
Nature Methods, Published online: 2024-03-13; | doi:10.1038/s41592-024-02209-6
2024-03-13
Nature Methods
10.1038/s41592-024-02209-6
https://www.nature.com/articles/s41592-024-02209-6
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https://www.nature.com/articles/s41592-024-02219-4
Nature Methods, Published online: 12 March 2024; doi:10.1038/s41592-024-02219-4Graphene sandwich for cryo-EM]]>
Arunima Singh
doi:10.1038/s41592-024-02219-4
Nature Methods, Published online: 2024-03-12; | doi:10.1038/s41592-024-02219-4
2024-03-12
Nature Methods
10.1038/s41592-024-02219-4
https://www.nature.com/articles/s41592-024-02219-4
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https://www.nature.com/articles/s41592-024-02221-w
Nature Methods, Published online: 12 March 2024; doi:10.1038/s41592-024-02221-wA leap for directed evolution]]>
Rita Strack
doi:10.1038/s41592-024-02221-w
Nature Methods, Published online: 2024-03-12; | doi:10.1038/s41592-024-02221-w
2024-03-12
Nature Methods
10.1038/s41592-024-02221-w
https://www.nature.com/articles/s41592-024-02221-w
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https://www.nature.com/articles/s41592-024-02218-5
Nature Methods, Published online: 12 March 2024; doi:10.1038/s41592-024-02218-5Neural networks for biomechanics]]>
Madhura Mukhopadhyay
doi:10.1038/s41592-024-02218-5
Nature Methods, Published online: 2024-03-12; | doi:10.1038/s41592-024-02218-5
2024-03-12
Nature Methods
10.1038/s41592-024-02218-5
https://www.nature.com/articles/s41592-024-02218-5
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https://www.nature.com/articles/s41592-024-02220-x
Nature Methods, Published online: 12 March 2024; doi:10.1038/s41592-024-02220-xLong-term monosynaptic tracing]]>
Nina Vogt
doi:10.1038/s41592-024-02220-x
Nature Methods, Published online: 2024-03-12; | doi:10.1038/s41592-024-02220-x
2024-03-12
Nature Methods
10.1038/s41592-024-02220-x
https://www.nature.com/articles/s41592-024-02220-x