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Modeling cellular signaling: taking space into the computation

In living systems, chemical reactions and the geometry of cells feed back on each other. Methods for computational modeling are beginning to take this complexity into account.

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Figure 1: Combination of rule-based modeling with dynamic cellular geometries.

Katie Vicari

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Correspondence to Thierry Emonet.

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Sneddon, M., Emonet, T. Modeling cellular signaling: taking space into the computation. Nat Methods 9, 239–242 (2012). https://doi.org/10.1038/nmeth.1900

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