Researchers use light-activated photo-uncaging to dissect the elementary steps in protein kinase signaling networks in living human cells.
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References
Gautier, A. et al. Light-activated kinases enable temporal dissection of signaling networks in living cells. J. Am. Chem. Soc. 133, 2124–2127 (2011).
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Doerr, A. Dissecting signaling at the speed of light. Nat Methods 8, 284–285 (2011). https://doi.org/10.1038/nmeth0411-284b
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DOI: https://doi.org/10.1038/nmeth0411-284b