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Correcting distorted optics: back to the basics

A surprisingly simple method provides an effective way of correcting optical distortions in two-photon fluorescence microscopy and recovers nearly ideal images of inhomogeneous thick samples.

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Figure 1: Optical aberrations cause subaperture focus displacements.

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Heintzmann, R. Correcting distorted optics: back to the basics. Nat Methods 7, 108–110 (2010). https://doi.org/10.1038/nmeth0210-108

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