1. Matthias Stadtfeld and Konrad Hochedlinger are in the Department of Medicine, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA. e-mail: khochedlinger@helix.mgh.harvard.edu or e-mail: mstadtfeld@mgh.harvard.edu

Abstract

A transposon-based approach has been added to the growing arsenal of technologies to produce transgene-free and potentially safer induced pluripotent stem cells.

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