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Nature Methods 5, 761–762 (1 September 2008) | doi:10.1038/nmeth0908-761
Genetically encoded Ca2+ sensors come of age
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Abstract
A particularly elegant method for the exploration of brain function relies on the detection of changes in intracellular Ca2+ concentration in neurons with fluorometric sensors. Action-potential firing is invariably associated with transient elevations in intracellular Ca2+ concentration.
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