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Nature Methods 5, 759–760 (1 September 2008) | doi:10.1038/nmeth0908-759

Sex to the rescue

Thomas J Silhavy & Zemer Gitai

A comprehensive understanding of the cellular functions of every gene and gene network is a primary goal of the post-genomic era. Analysis of double-mutant phenotypes has long been appreciated as a powerful approach for realizing this goal.