Abstract
Applying a classical solution to a cutting-edge problem, two groups used bacterial conjugation to construct Escherichia coli double mutants on a genome-wide scale. This will allow comprehensive genetic interaction screens in bacteria for the first time.
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Silhavy, T., Gitai, Z. Sex to the rescue. Nat Methods 5, 759–760 (2008). https://doi.org/10.1038/nmeth0908-759
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DOI: https://doi.org/10.1038/nmeth0908-759
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