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Nature Methods 5, 383–384 (1 May 2008) | doi:10.1038/nmeth0508-383
BAC to the future: functional genomics in mammals
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Abstract
DNA engineering technology, allowing one to assemble DNA fragments like Lego pieces, has revolutionized biology. In this issue, Poser, Sarov and colleagues describe the BAC TransgeneOmics pipeline—a generic, high-throughput methodology that allows for the rapid generation of large DNA constructs, which will facilitate systematic characterization of protein function in mammals.
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