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Nature Methods
ISSUE
April 2008, Volume 5 No 4
In This Issue
Editorial
Correspondence
Research Highlights
Commentary
News and Views
Brief Communications
Articles
Protocol
Technology Feature
Addendum
Application Notes
About the cover
In This Issue Top
PDF
Editorial Top
Compare and conquer p275
doi:10.1038/nmeth0408-275
Abstract | Full text | PDF (63K)
Correspondence Top
Cyclic nucleotide analogs as probes of signaling pathways pp277 - 278
Heiko Poppe, Sergei D Rybalkin, Holger Rehmann, Thomas R Hinds, Xiao-Bo Tang, Anne E Christensen, Frank Schwede, Hans-Gottfried Genieser, Johannes L Bos, Stein O Doskeland, Joseph A Beavo & Elke Butt
doi:10.1038/nmeth0408-277
Full text | PDF (98K)  | Supplementary Information
Whole genome–amplified DNA: insights and imputation pp279 - 280
Yik Y Teo, Michael Inouye, Kerrin S Small, Andrew E Fry, Simon C Potter, Sarah J Dunstan, Mark Seielstad, Inês Barroso, Nicholas J Wareham, Kirk A Rockett, Dominic P Kwiatkowski & Panos Deloukas
doi:10.1038/nmeth0408-279
Full text | PDF (3,681K)  | Supplementary Information
ADVERTISEMENT
Research Highlights Top
Protein suicide highlights the cell cycle p283
Daniel Evanko
doi:10.1038/nmeth0408-283
Abstract | Full text | PDF (185K)
Mapping the plant methylome pp284 - 285
Nicole Rusk
doi:10.1038/nmeth0408-284a
Abstract | Full text | PDF (128K)
Insulating gene expression pp284 - 285
Katherine Stevens
doi:10.1038/nmeth0408-284b
Abstract | Full text | PDF (128K)
News in brief p285
doi:10.1038/nmeth0408-285
Full text | PDF (75K)
DNA synthesis lights up p286
Allison Doerr
doi:10.1038/nmeth0408-286
Abstract | Full text | PDF (142K)
ChIP-chip put to the test p288
Veronique Kiermer
doi:10.1038/nmeth0408-288
Abstract | Full text | PDF (83K)
Commentary Top
Disaccharide structure code for the easy representation of constituent oligosaccharides from glycosaminoglycans pp291 - 292
Roger Lawrence, Hong Lu, Robert D Rosenberg, Jeffrey D Esko & Lijuan Zhang
doi:10.1038/nmeth0408-291
Abstract | Full text | PDF (113K)
News and Views Top
Expanding the toolbox for remote control of neuronal circuits pp293 - 295
Thomas Knöpfel
doi:10.1038/nmeth0408-293
Abstract | Full text | PDF (3,608K)
See also: Brief Communication by Arenkiel et al.  | Article by Fortin et al.
SNPing and chipping away at the fly genome pp295 - 296
Steven Russell
doi:10.1038/nmeth0408-295
Abstract | Full text | PDF (1,103K)
See also: Article by Chen et al.
Levers and fulcrums: progress in cis-regulatory motif models pp297 - 298
Ewan Birney
doi:10.1038/nmeth0408-297
Abstract | Full text | PDF (235K)
See also: Article by Warner et al.
Brief Communications Top
Genetic control of neuronal activity in mice conditionally expressing TRPV1 pp299 - 302
Benjamin R Arenkiel, Marguerita E Klein, Ian G Davison, Lawrence C Katz & Michael D Ehlers
Published online: 09 March 2008 | doi:10.1038/nmeth.1190
Abstract | Full text | PDF (293K)  | Supplementary Information
See also: News and Views by Knöpfel
Activation of protein splicing with light in yeast pp303 - 305
Amy B Tyszkiewicz & Tom W Muir
Published online: 13 February 2008 | doi:10.1038/nmeth.1189
Abstract | Full text | PDF (224K)  | Supplementary Information
Genome-wide mapping of allele-specific protein-DNA interactions in human cells pp307 - 309
Nathaniel D Maynard, Jing Chen, Rhona K Stuart, Jian-Bing Fan & Bing Ren
Published online: 16 March 2008 | doi:10.1038/nmeth.1194
Abstract | Full text | PDF (178K)  | Supplementary Information
In vivo immunogold labeling confirms large-scale chromatin folding motifs pp311 - 313
Igor Kireev, Margot Lakonishok, Wenqiu Liu, Vishwas N Joshi, Rick Powell & Andrew S Belmont
Published online: 16 March 2008 | doi:10.1038/nmeth.1196
Abstract | Full text | PDF (328K)  | Supplementary Information
Identification of cross-linked peptides from large sequence databases pp315 - 318
Oliver Rinner, Jan Seebacher, Thomas Walzthoeni, Lukas N Mueller, Martin Beck, Alexander Schmidt, Markus Mueller & Ruedi Aebersold
Published online: 09 March 2008 | doi:10.1038/nmeth.1192
Abstract | Full text | PDF (373K)  | Supplementary Information
A quantitative analysis software tool for mass spectrometry–based proteomics pp319 - 322
Sung Kyu Park, John D Venable, Tao Xu & John R Yates III
Published online: 16 March 2008 | doi:10.1038/nmeth.1195
Abstract | Full text | PDF (347K)  | Supplementary Information
Articles Top
High-resolution, high-throughput SNP mapping in Drosophila melanogaster pp323 - 329
Doris Chen, Annika Ahlford, Frank Schnorrer, Irene Kalchhauser, Michaela Fellner, Erika Viràgh, Istvàn Kiss, Ann-Christine Syvänen & Barry J Dickson
Published online: 09 March 2008 | doi:10.1038/nmeth.1191
Abstract | Full text | PDF (766K)  | Supplementary Information
See also: News and Views by Russell
Photochemical control of endogenous ion channels and cellular excitability pp331 - 338
Doris L Fortin, Matthew R Banghart, Timothy W Dunn, Katharine Borges, Daniel A Wagenaar, Quentin Gaudry, Movses H Karakossian, Thomas S Otis, William B Kristan, Dirk Trauner & Richard H Kramer
Published online: 02 March 2008 | doi:10.1038/nmeth.1187
Abstract | Full text | PDF (583K)  | Supplementary Information
See also: News and Views by Knöpfel
Direct measurement of protein dynamics inside cells using a rationally designed photoconvertible protein pp339 - 345
Tomoki Matsuda, Atsushi Miyawaki & Takeharu Nagai
Published online: 16 March 2008 | doi:10.1038/nmeth.1193
Abstract | Full text | PDF (627K)  | Supplementary Information
Systematic identification of mammalian regulatory motifs' target genes and functions pp347 - 353
Jason B Warner, Anthony A Philippakis, Savina A Jaeger, Fangxue Sherry He, Jolinta Lin & Martha L Bulyk
Published online: 02 March 2008 | doi:10.1038/nmeth.1188
Abstract | Full text | PDF (551K)  | Supplementary Information
See also: News and Views by Birney
Protocol Top
A sensitive direct human telomerase activity assay pp355 - 360
Scott B Cohen & Roger R Reddel
Published online: 28 March 2008 | doi:10.1038/nmeth.f.209
Abstract | Full text | PDF (267K)  | Supplementary Information
Technology Feature Top
RNAi technologies: a screen whose time has arrived pp361 - 368
Nathan Blow
doi:10.1038/nmeth0408-361
Abstract | Full text | PDF (331K)
Addendum Top
Addendum: Protein production and purification p369
Structural Genomics Consortium, Architecture et Fonction des Macromolécules Biologiques, Berkeley Structural Genomics Center, China Structural Genomics Consortium, Integrated Center for Structure and Function Innovation, Israel Structural Proteomics Center, Joint Center for Structural Genomics, Midwest Center for Structural Genomics, New York Structural GenomiX Research Center for Structural Genomics, Northeast Structural Genomics Consortium, Oxford Protein Production Facility, Protein Sample Production Facility, Max Delbrück Center for Molecular Medicine, RIKEN Structural Genomics/Proteomics Initiative & SPINE2-Complexes
doi:10.1038/nmeth0408-369
Full text | PDF (47K)
Application Notes Top
Refining epifluorescence imaging and analysis with automated multiple-band flat-field correction 
Douglas Wood, Gilbert Feke, Douglas Vizard & Rao Papineni

Abstract | Full text | PDF (307K)
Selecting a cyclic AMP kit for assaying GPCR target activation 
Jean-Luc Tardieu

Abstract | Full text | PDF (172K)
  Top

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ISSN: 1548-7091
EISSN: 1548-7105
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