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Insulating gene expression

Abstract

In an analysis of transgene insertion sites, researchers find that position effects cause tissue-specific expression of transgenes but that insulators allow uniform expression.

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References

  1. Markstein, M. et al. Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes. Nat. Genet., published online 2 March 2008.

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Stevens, K. Insulating gene expression. Nat Methods 5, 284–285 (2008). https://doi.org/10.1038/nmeth0408-284b

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  • DOI: https://doi.org/10.1038/nmeth0408-284b

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