Abstract
In an analysis of transgene insertion sites, researchers find that position effects cause tissue-specific expression of transgenes but that insulators allow uniform expression.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Markstein, M. et al. Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes. Nat. Genet., published online 2 March 2008.
Rights and permissions
About this article
Cite this article
Stevens, K. Insulating gene expression. Nat Methods 5, 284–285 (2008). https://doi.org/10.1038/nmeth0408-284b
Issue Date:
DOI: https://doi.org/10.1038/nmeth0408-284b