Nature Methods

Volume 5 Issue 3, March 2008

Holstein cow with a calf. Image from iStockphoto and adapted by Erin Boyle. Article, p247

Volume 5 Issue 3

Editorial

Thou shalt share your data

Starting this month, Nature Methods strongly recommends deposition of proteomics data to public repositories before manuscript submission.

Editorial 01 Mar 2008

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Correspondence

Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking

Ryuichiro Atarashi
Jason M Wilham
Byron Caughey
Correspondence 01 Mar 2008
GFP fails to inhibit actin-myosin interactions in vitro

Daniel I Resnicow
Anneka M Hooft
Leslie A Leinwand
Correspondence 01 Mar 2008
Reply to “GFP fails to inhibit actin-myosin interactions in vitro”

Onnik Agbulut
Catherine Coirault
Michel Puceat
Correspondence 01 Mar 2008
Pitfalls of measuring feeding rate in the fruit fly Drosophila melanogaster

Richard Wong
Matthew D W Piper
Linda Partridge
Correspondence 01 Mar 2008
Reply to “Pitfalls of measuring feeding rate in the fruit fly Drosophila melanogaster”

Gil B Carvalho
William W Ja
Seymour Benzer
Correspondence 01 Mar 2008

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Research Highlights

Networking an organism

Natalie de Souza
Research Highlights 01 Mar 2008
The new fluorescent probes on the block

Daniel Evanko
Research Highlights 01 Mar 2008
Sugars direct stem cell homing

Nicole Rusk
Research Highlights 01 Mar 2008
News in brief

Research Highlights 01 Mar 2008
RNA antibodies: upping the ante

Allison Doerr
Research Highlights 01 Mar 2008
An origami chip of DNA

Irene Kaganman
Research Highlights 01 Mar 2008

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News & Views

Harnessing mismatch repair to model sporadic cancers

Two mouse models that initiate sporadic tumors seek to recapitulate spontaneously arising human cancers.

Richard Fishel
Joanna Groden
News & Views 01 Mar 2008

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Brief Communication

Tractable Cre-lox system for stochastic alteration of genes in mice

Ashleigh J Miller
Sandra D Dudley
R Michael Liskay
Brief Communication 10 Feb 2008
Generating somatic mosaicism with a Cre recombinase–microsatellite sequence transgene

Aytekin Akyol
Takao Hinoi
Eric R Fearon
Brief Communication 10 Feb 2008
Error-correcting barcoded primers for pyrosequencing hundreds of samples in multiplex

Micah Hamady
Jeffrey J Walker
Rob Knight
Brief Communication 10 Feb 2008
A systematic library for comprehensive overexpression screens in Saccharomyces cerevisiae

Grace Marie Jones
Jim Stalker
Gregory Prelich
Brief Communication 03 Feb 2008
Extending the NMR spatial resolution limit for RNA by motional couplings

Qi Zhang
Hashim M Al-Hashimi
Brief Communication 03 Feb 2008

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Article

SNP discovery and allele frequency estimation by deep sequencing of reduced representation libraries

Curtis P Van Tassell
Timothy P L Smith
Tad S Sonstegard
Article 24 Feb 2008
Homogeneous reporter system enables quantitative functional assessment of multiple transcription factors

Sergei Romanov
Alexander Medvedev
Sergei Makarov
Article 24 Feb 2008

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Protocol

Induction of linear tracks of DNA double-strand breaks by α-particle irradiation of cells

Jan Stap
Przemek M Krawczyk
Jacob A Aten
Protocol 28 Feb 2008

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Technology Feature

DNA sequencing: generation next-next

Emboldened by the success of next-generation sequencing, scientists are pursuing the holy grail of genomics—the '$1,000 genome'—with single-molecule approaches. Nathan Blow reports.

Nathan Blow
Technology Feature 01 Mar 2008

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Advertising Feature: Application Note

The LightCycler^® 480 real-time PCR system: a versatile platform for genetic variation research

Michael Hoffmann
Oliver Geulen
Christian Weilke
Advertising Feature: Application Note 01 Mar 2008
SilenciX cell lines for valuable insights into cellular pathways

Nadia Normand
Advertising Feature: Application Note 01 Mar 2008

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