Protein production and purification

Structural Genomics Consortium^1,2,3, Architecture et Fonction des Macromolécules Biologiques⁴, Berkeley Structural Genomics Center⁵, China Structural Genomics Consortium^6,7, Integrated Center for Structure and Function Innovation⁸, Israel Structural Proteomics Center⁹, Joint Center for Structural Genomics^10,11, Midwest Center for Structural Genomics¹², New York Structural GenomiX Research Center for Structural Genomics^{13,14,15,16,17}, Northeast Structural Genomics Consortium^18,19, Oxford Protein Production Facility²⁰, Protein Sample Production Facility, Max Delbrück Center for Molecular Medicine²¹, RIKEN Structural Genomics/Proteomics Initiative²² & SPINE2-Complexes^23,25

¹  Karolinska Institutet, Schéeles väg 2, 171 77 Stockholm, Sweden.

²  University of Oxford, Old Road Campus, Roosevelt Drive, Headington, Oxford OX3 7DQ, UK.

³  University of Toronto, 100 College St., Toronto, Ontario M5G 1L6, Canada.

⁴  Architecture et Fonction des Macromolécules Biologiques, Centre National de la Recherche Scientifique, Case 932, 163 Avenue de Luminy, 13288 Marseille Cedex 09, France.

⁵  Lawrence Berkeley National Laboratory and Department of Chemistry, University of California, 351A Donner Laboratory, Berkeley, California 94720, USA.

⁶  Tsinghua University, Beijing 100084, China.

⁷  University of Science and Technology of China, Hefei 230027, China.

⁸  Los Alamos National Laboratory, Mailstop M888, Los Alamos, New Mexico 87507, USA.

⁹  Weizmann Institute of Science, 2 Herzel Street, Rehovot 76100, Israel.

¹⁰  The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, California 92037, USA.

¹¹  Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California, 92121, USA.

¹²  Biosciences Division, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, Illinois 60439, USA.

¹³  SGX Pharmaceuticals, Inc., 10505 Roselle Street, San Diego, California 92121, USA.

¹⁴  Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

¹⁵  Biology Department, 463, Brookhaven National Laboratory, Upton, New York 11973, USA.

¹⁶  Case Western Reserve University, 10900 Euclid Ave., Cleveland, Ohio 44016, USA.

¹⁷  Departments of Biopharmaceutical Sciences and Pharmaceutical Chemistry, University of California, San Francisco, 600 16th Street, San Francisco, California 94143, USA.

¹⁸  Center for Advanced Biotechnology and Medicine, Rutgers University, 679 Hoes Lane, Piscataway, New Jersey 08854, USA.

¹⁹  Department of Biological Sciences, Columbia University, 701 Fairchild Building, MC 2451, New York, New York 10027, USA.

²⁰  Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX37BN, UK.

²¹  Max Delbrück Center for Molecular Medicine (MDC), Robert-Rössle-Str. 10, 13092 Berlin, Germany,

²²  Protein Research Group, Genomic Sciences Center, Yokohama Institute, RIKEN, 1-7-22 Suehiro-cho, Tsurumi, Yokohama 230-0045, Japan.

²³  Division of Structural Biology, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX37BN, UK.

²⁴  Present addresses: Structural Biology, Helmoltz Center for Infection Research, Inhoffenstr. 7, 38124 Braunschweig, Germany (K.B.), and Department of Biology, and Center for Genomics and Systems Biology, New York University, 1009 Sliver Center, 100 Washington Square East, New York, NY 10003, USA (K.C.G.).

²⁵  A complete list of authors appears at the end of this paper.

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