Nature Methods
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Figure 1

Nature Methods - 5, 6 - 7 (2008)
doi:10.1038/nmeth0108-6a

Chemical biology

Smaller can be better

Allison Doerr

 
Fig 1 full size
Figure 1. Bipartite tetracysteine display can distinguish between folded and misfolded proteins.
The folded protein (top) has a high affinity for ReAsH and forms a brightly fluorescent complex. The misfolded protein (bottom) has a much lower affinity for ReAsH and forms a dim complex. Reprinted from Nature Chemical Biology.

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