Luminescent conjugated polymers (LCPs) bind to prion aggregates and emit different fluorescent spectra depending on their binding conformation. As such, they are promising tools for investigating the biophysical basis of prion strains.
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Jackson, W., Lindquist, S. Illuminating aggregate heterogeneity in neurodegenerative disease. Nat Methods 4, 1000–1001 (2007). https://doi.org/10.1038/nmeth1207-1000
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DOI: https://doi.org/10.1038/nmeth1207-1000
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