Nature Methods
- 4, 1000 - 1001 (2007)
doi:10.1038/nmeth1207-1000
Illuminating aggregate heterogeneity in neurodegenerative diseaseWalker S Jackson & Susan Lindquist
Walker S. Jackson and Susan Lindquist are at the Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA. Susan Lindquist is also at Howard Hughes Medical Institute and the Massachusetts Institute of Technology, Department of Biology, Cambridge, Massachusetts 02142, USA. lindquist_admin@wi.mit.edu
Luminescent conjugated polymers (LCPs) bind to prion aggregates and emit different fluorescent spectra depending on their binding conformation. As such, they are promising tools for investigating the biophysical basis of prion strains.
MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated.
|
