Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

How to find an opening (or lots of them)

DNase-chip and DNase-array: similar names for two different new approaches that give a genomic perspective to the conventional DNase I hypersensitivity assay used to measure chromatin accessibility.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Methods for detecting DNase I hypersensitive sites.

Katie Ris

References

  1. Felsenfeld, G. & Groudine, M. Nature 421, 448–453 (2003).

    Article  Google Scholar 

  2. Gross, D.S. & Garrard, W.T. Annu. Rev. Biochem. 57, 159–197 (1988).

    Article  CAS  Google Scholar 

  3. McGhee, J.D., Wood, W.I., Dolan, M., Engel, J.D. & Felsenfeld, G. Cell 27, 45–55 (1981).

    Article  CAS  Google Scholar 

  4. Keene, M.A., Corces, V., Lowenhaupt, K. & Elgin, S.C. Proc. Natl. Acad. Sci. USA 78, 143–146 (1981).

    Article  CAS  Google Scholar 

  5. Crawford, G.E. et al. Nat. Methods 3, 503–509 (2006).

    Article  CAS  Google Scholar 

  6. Sabo, P.J. et al. Nat. Methods 3, 511–518 (2006).

    Article  CAS  Google Scholar 

  7. Boeger, H., Griesenbeck, J., Strattan, J.S. & Kornberg, R.D. Mol. Cell. 11, 1587–1598 (2003).

    Article  CAS  Google Scholar 

  8. Varga-Weisz, P. Oncogene 20, 3076–3085 (2001).

    Article  CAS  Google Scholar 

  9. Pauli, U., Chrysogelos, S., Nick, H., Stein, G. & Stein, J. Nucleic Acids Res. 17, 2333–2350 (1989).

    Article  CAS  Google Scholar 

  10. ENCODE Project Consortium. Science 306, 636–640 (2004).

  11. Sabo, P.J. et al. Proc. Natl. Acad. Sci. USA 101, 16837–16842 (2004).

    Article  CAS  Google Scholar 

  12. Sabo, P.J. et al. Proc. Natl. Acad. Sci. USA 101, 4537–4542 (2004).

    Article  CAS  Google Scholar 

  13. Crawford, G.E. et al. Genome Res 16, 123–131 (2006).

    Article  CAS  Google Scholar 

  14. Crawford, G.E. et al. Proc. Natl. Acad. Sci. USA 101, 992–997 (2004).

    Article  CAS  Google Scholar 

  15. Katayama, S. et al. Science 309, 1564–1566 (2005).

    Article  Google Scholar 

  16. Martin, M., Cho, J., Cesare, A.J., Griffith, J.D. & Attardi, G. Cell 123, 1227–1240 (2005).

    Article  CAS  Google Scholar 

  17. Liu, Z. & Garrard, W.T. Mol. Cell. Biol. 25, 3220–3231 (2005).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Giresi, P., Lieb, J. How to find an opening (or lots of them). Nat Methods 3, 501–502 (2006). https://doi.org/10.1038/nmeth0706-501

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmeth0706-501

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing