Nature Methods
- 3, 973 - 975 (2006)
doi:10.1038/nmeth1206-973
Atomic force microscopy of membrane proteins separating two aqueous compartmentsYves F Dufrêne
Yves F. Dufrêne is at the Unité de chimie des interfaces, Nanobio team, Université catholique de Louvain, Croix du Sud 2/18, B-1348 Louvain-la-Neuve, Belgium. dufrene@cifa.ucl.ac.be
A novel atomic force microscopy (AFM) setup allows researchers to image and manipulate unsupported membrane proteins separating two aqueous compartments. This promises to permit new detailed measurements of protein conformational changes and interactions under native-like conditions.
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