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Transgenic Caenorhabditis elegans reporter worms displaying patterns of alternative mRNA splicing in vivo. Cover by Erin Boyle, using images provided by Hidehito Kuroyanagi. Article p909
They may be tiny, but microRNAs show strength in numbers and by exerting a surprising amount of influence over the expression of many genes. In the space of just a few years, the identification and analysis of microRNAs has become a boom industry, necessitating new tools and techniques suitable for such small targets. Michael Eisenstein reports.
