Nature Methods
- 3, 825 - 831 (2006)
Published online: 21 September 2006; | doi:10.1038/nmeth931
State-based discovery: a multidimensional screen for small-molecule modulators of EGF signalingMark Sevecka & Gavin MacBeath Supplementary Fig. 1 (pdf 304K) Evaluation of antibodies for lysate microarrays. Supplementary Fig. 2 (pdf 56K) Verification of compound activities using traditional western blotting. Supplementary Table 1 (pdf 60K) Antibodies used in the state-based screen. Supplementary Table 2 (pdf 16K) Identity of compounds in the model library. Supplementary Methods (pdf 72K) Reagents, cell culture, immunoblotting, and determination of dose-response behavior. Supplementary Note (pdf 100K) Data processing steps used in the state-based screen and how these steps affect uncertainty in the data.
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