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Article
Nature Methods - 3, 825 - 831 (2006)
Published online: 21 September 2006; | doi:10.1038/nmeth931

State-based discovery: a multidimensional screen for small-molecule modulators of EGF signaling

Mark Sevecka & Gavin MacBeath

Supplementary Fig. 1 (pdf 304K)
Evaluation of antibodies for lysate microarrays.

Supplementary Fig. 2 (pdf 56K)
Verification of compound activities using traditional western blotting.

Supplementary Table 1 (pdf 60K)
Antibodies used in the state-based screen.

Supplementary Table 2 (pdf 16K)
Identity of compounds in the model library.

Supplementary Methods (pdf 72K)
Reagents, cell culture, immunoblotting, and determination of dose-response behavior.

Supplementary Note (pdf 100K)
Data processing steps used in the state-based screen and how these steps affect uncertainty in the data.


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Nature Methods
ISSN: 1548-7091
EISSN: 1548-7105
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