Nature Methods
2, 691 - 697 (2005)
Published online: 23 August 2005; | doi:10.1038/nmeth778
A streamlined platform for high-content functional proteomics of primary human specimensNadim Jessani, Sherry Niessen, BinQing Q Wei, Monica Nicolau, Mark Humphrey, Youngran Ji, Wonshik Han, Dong-Young Noh, John R Yates III, Stefanie S Jeffrey
& Benjamin F Cravatt Supplementary Fig. 1 (pdf 360K)
Structures of fluorophosphonate (FP) ABPP probes. Supplementary Fig. 2 (pdf 3M)
Enzyme activity profiles for primary human breast tumor and normal breast specimens determined by 1D-gel ABPP. Supplementary Fig. 3 (pdf 2M)
Representative gel showing molecular mass annotations of enzyme activities used in the clustering analysis shown in Figure 2b of the manuscript. Supplementary Fig. 4 (pdf 316K)
Gene expression profiles for differentially expressed enzyme activities in primary human breast tumor and normal breast specimens. Supplementary Table 1 (pdf 68K)
Clinical data on breast tumors. Supplementary Table 2 (pdf 68K)
A complete list of the FP-labeled serine hydrolase activities identified in primary human breast tumor and normal breast specimens. Supplementary Table 3 (pdf 44K)
Reproducibility of enzyme activity data for ER(-)/PR(-) breast tumor BC48. Supplementary Methods (pdf 276K)
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