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Article
Nature Methods  2, 345 - 350 (2005)
Published online: 21 April 2005; | doi:10.1038/nmeth756

Multiple-laboratory comparison of microarray platforms

Rafael A Irizarry, Daniel Warren, Forrest Spencer, Irene F Kim, Shyam Biswal, Bryan C Frank, Edward Gabrielson, Joe G N Garcia, Joel Geoghegan, Gregory Germino, Constance Griffin, Sara C Hilmer, Eric Hoffman, Anne E Jedlicka, Ernest Kawasaki, Francisco Martínez-Murillo, Laura Morsberger, Hannah Lee, David Petersen, John Quackenbush, Alan Scott, Michael Wilson, Yanqin Yang, Shui Qing Ye & Wayne Yu

Supplementary Fig. 1 (pdf 676K)
Observed log fold change versus RT-PCR log fold change for the four altered genes and 12 selected genes.

Supplementary Fig. 2 (pdf 1M)
Preprocessing effect.

Supplementary Fig. 3 (pdf 464K)
SD (measure of precision) plotted against experience of technician for each of the five Affymetrix labs.

Supplementary Fig. 4 (pdf 476K)
Precision assessment for the new Affymetrix chip.

Supplementary Table 1 (pdf 56K)
Within and across lab assessment measure comparing preprocessing procedures as for Supplementary Figure 2.

Supplementary Table 2 (pdf 60K)
Effect of annotation on across-lab agreement.

Supplementary Table 3 (pdf 64K)
Across-lab agreement.

Supplementary Table 4 (pdf 52K)
Assessments for results from lab 5 using old and new chip compared to results from the best performing labs.

Supplementary Methods (pdf 68K)


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Nature Methods
ISSN: 1548-7091
EISSN: 1548-7105
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