Stuart J. Smith and Timothy J. Mohun are in the Developmental Biology Division, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK. tmohun@nimr.mrc.ac.uk
A Xenopus embryo coinjected with a plasmid encoding a transgene and the C31 integrase mRNA readily facilitates genomic integration resulting in healthy transgenic embryos.
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