In living color: DNA methyltransferase caught in the act
Kornel Schuebel
& Steve Baylin
Kornel Schuebel and Steve Baylin are at the Laboratory of Cancer Biology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, 1650 Orleans Street, Baltimore, Maryland 21231, USA.
kornels@jhmi.edu
Since the 1970s, fluorescence recovery after photobleaching has advanced our understanding of cell membrane dynamics and cytoplasmic signaling pathways. This technique has now been applied in the nucleus to address questions in epigenetics and provides a useful new tool to develop pharmacotherapies for human disease.
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