Sleeping Beauty hits them all: transposon-mediated saturation mutagenesis in the mouse germline
Zsuzsanna Izsvák
& Zoltán Ivics
Zsuzsanna Izsvák and Zoltán Ivics are at the Max Delbrück Center for Molecular Medicine, Berlin, Germany.
zivics@mdc-berlin.de
The Sleeping Beauty (SB) transposon emerged as a useful tool for applications such as germline and somatic cell insertional mutagenesis and now shows its usefulness again by facilitating saturating germline mutagenesis in mice.
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