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Commentary
Nature Methods  2, 731 - 734 (2005)
doi:10.1038/nmeth1005-731

The External RNA Controls Consortium: a progress report

The External RNA Controls Consortium: Shawn C Baker1, Steven R Bauer2, Richard P Beyer3, James D Brenton4, Bud Bromley5, John Burrill6, Helen Causton7, Michael P Conley8, Rosalie Elespuru9, Michael Fero10, Carole Foy11, James Fuscoe12, Xiaolian Gao13, David Lee Gerhold14, Patrick Gilles15, Federico Goodsaid16, Xu Guo17, Joe Hackett18, Richard D Hockett19, Pranvera Ikonomi20, Rafael A Irizarry21, Ernest S Kawasaki22, Tamma Kaysser-Kranich23, Kathleen Kerr3, Gretchen Kiser23, Walter H Koch24, Kathy Y Lee24, Chunmei Liu17, Z Lewis Liu25, Anne Lucas26, Chitra F Manohar27, Garry Miyada17, Zora Modrusan28, Helen Parkes11, Raj K Puri29, Laura Reid30, Thomas B Ryder17, Marc Salit31, Raymond R Samaha6, Uwe Scherf32, Timothy J Sendera6, Robert A Setterquist33, Leming Shi12, Richard Shippy23, Jesus V Soriano34, Elizabeth A Wagar35, Janet A Warrington17, Mickey Williams24, Frederike Wilmer36, Mike Wilson33, Paul K Wolber26, Xiaoning Wu24 & Renata Zadro37

1  Illumina, Inc., 9885 Towne Centre Drive, San Diego, California 92121, USA.

2  US Food and Drug Administration, Center for Biologics Evaluation and Research, Building 29B/2NN12, HFM-521, 1401 Rockville Pike, Rockville, Maryland 20852, USA.

3  University of Washington, 4225 Roosevelt Way NE, Seattle, Washington 98105, USA.

4  Cambridge University, Cambridge Institute for Medical Research (CIMR), Wellcome Trust/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, UK.

5  ViaLogy Corporation, 2400 Lincoln Avenue, Altadena, California 91001, USA.

6  Applied Biosystems, 850 Lincoln Center Drive, Foster City, California 94404, USA.

7  University of London, Imperial College of London, London SW7 2AZ, UK.

8  Enzo Life Sciences, Inc., 60 Executive Boulevard, Farmingdale, New York 11735, USA.

9  US Food and Drug Administration, Center for Devices and Radiological Health, Federal Laboratories at White Oak, Life Sciences Building 64, Room 3020, 10903 New Hampshire Avenue, Silver Spring, Maryland 20903, USA.

10  Stanford University School of Medicine, CCSR 4256, 269 Campus Drive, Stanford, California 94305, USA.

11  LGC, Bio-Molecular Innovation, Queens Road, Teddington TW11OLY, UK.

12  US Food and Drug Administration, National Center for Toxicological Research, 3900 NCTR Road, HFT-020, Jefferson, Arkansas 72079, USA.

13  Atactic Technology, Inc., 2575 W. Bellfort, Suite 270, Houston, Texas 77054, USA.

14  Merck Research Laboratories, Department of Molecular Profiling, West Point, Pennsylvania 19486, USA.

15  Invitrogen Corporation, 1600 Faraday Avenue, P.O. Box 6482, Carlsbad, California 92008, USA.

16  US Food and Drug Administration, Center for Drug Evaluation and Research, 1451 Rockville Pike (HFD-860), Woodmont II Office 2078, Rockville, Maryland 20852, USA.

17  Affymetrix Inc., 3380 Central Expressway, Santa Clara, California 95051, USA.

18  US Food and Drug Administration, Center for Devices and Radiological Health, HFZ-440, 2098 Oak Grove, Rockville, Maryland 20850, USA.

19  Eli Lilly and Company, Lilly Research Lab, Lilly Corporate Center, Indianapolis, Indiana 46285, USA.

20  American Type Culture Collection, 10801 University Boulevard, Manassas, Virginia 20110, USA.

21  Johns Hopkins School of Public Health, 615 N. Wolfe St. E3132, Baltimore, Maryland 21205, USA.

22  National Cancer Institute Advanced Technology Center, National Institutes of Health, 8717 Grovemont Circle, Bethesda, Maryland 20892, USA.

23  GE Healthcare, 3200 W. Germann Road, Chandler, Arizona 85248, USA.

24  Roche Molecular Systems, 4300 Hacienda Dr., Pleasanton, California 94588, USA.

25  US Department of Ariculture, 1815 N. University Street, Peoria, Illinois 61604, USA.

26  Agilent Technologies, Inc., 5301 Stevens Creek Blvd. MS 55L WM, Santa Clara, California 95051, USA.

27  Lawrence Livermore National Laboratory Microarray Center, 7000 East Avenue, Livermore, California 94550, USA.

28  Genentech, 1 DNA Way, South San Francisco, California 94080, USA.

29  US Food and Drug Administration, NIH Building 29B, Room 2NN10, 29 Lincoln Drive MSC 4555, Bethesda, Maryland 20892, USA.

30  Expression Analysis, 2605 Meridian Parkway, Durham, North Carolina 27713, USA.

31  National Institute of Standards and Technology, Chemical Science and Technology Laboratory, 100 Bureau Drive, Stop 8391, Gaithersburg, Maryland 20899, USA.

32  US Food and Drug Administration, Office of In Vitro Diagnostic Device Evaluation and Safety, OAK8, RM366, HFZ-440, 2098 Gaither Road, Rockville, Maryland 20850, USA.

33  Ambion, Inc., 2130 Woodward St., Austin, Texas 78744, USA.

34  American Type Culture Collection, 10801 University Boulevard, Manassas, Virgnia 20110, USA.

35  UCLA Clinical Laboratories, 10833 Le Conte Avenue, Los Angeles, California 90095, USA.

36  Qiagen Inc., 40727 Hilden, Germany.

37  Zagreb University School of Medicine, Medical School, 10 000 Zagreb, Salata 3 Croatia.

Correspondence should be addressed to Janet A Warrington janet_warrington@affymetrix.com

Standard controls and best practice guidelines advance acceptance of data from research, preclinical and clinical laboratories by providing a means for evaluating data quality. The External RNA Controls Consortium (ERCC) is developing commonly agreed-upon and tested controls for use in expression assays, a true industry-wide standard control.

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Nature Methods
ISSN: 1548-7091
EISSN: 1548-7105
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