A simple tweak on the zygote's mitotic spindle generated hybrid Caenorhabditis elegans with certain tissues (such as those of the nervous system) consisting of entirely maternal genomes and others (such as the germline) consisting of entirely paternal genomes.
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References
Besseling, J. & Bringmann, H. Engineered non-Mendelian inheritance of entire parental genomes in C. elegans. Nat. Biotechnol. 34, 982–986 (2016).
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Gao, K. A nervous system from Mom and a gonad from Dad. Nat Methods 13, 812–813 (2016). https://doi.org/10.1038/nmeth.4017
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DOI: https://doi.org/10.1038/nmeth.4017