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Volume 12 Issue 10, October 2015

A mouse depicted on a radio-frequency transducer. The transducer activates optogenetic responses in the animal through an implanted light-delivery system. Cover by Erin Dewalt. Article p969

Editorial

  • Some cells have a remarkable capacity to organize into tissue-like structures in vitro. As methods to enable self-organization improve, ethical aspects of some of these experiments will need to be considered.

    Editorial

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This Month

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Correspondence

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Research Highlights

  • Developments in automated sample preparation, electron microscopy and data analysis enable in-depth characterization of a chunk of mouse neocortex.

    • Nina Vogt
    Research Highlights
  • Proximity ligation allows for the global resolution of RNA secondary structures.

    • Rita Strack
    Research Highlights
  • Researchers use chemistry to solve a nagging problem that has challenged the analysis of RNA from formaldehyde-fixed tissue specimens.

    • Allison Doerr
    Research Highlights
  • Fluorescent labeling of bacteria enables tracking of their location.

    • Irene Jarchum
    Research Highlights
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Methods in Brief

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Tools in Brief

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Research Highlights

  • An analytical algorithm for transcriptomic data reveals rare cell types that were previously hidden in larger populations.

    • Michael Eisenstein
    Research Highlights
  • Fusing ribosomal subunits provides answers to basic questions about their function and opens the door to exciting engineering possibilities.

    • Nicole Rusk
    Research Highlights
  • New protocols generate neurons directly from fibroblasts using only chemical cocktails.

    • Tal Nawy
    Research Highlights
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Commentary

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Technology Feature

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News & Views

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Brief Communication

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Article

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