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Volume 11 Issue 3, March 2014

The cover shows a sample of single-particle image data overlaid with tracking result trajectories from a competition to assess the performance of single-particle tracking algorithms. Image by Erik Meijering. Analysis p281

Editorial

  • The usefulness of computational methods can be improved by releasing code and designing software that supports reproducible research.

    Editorial

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This Month

  • A bass guitar helps a scientist-engineer promote transparency for bioimage analysis.

    • Vivien Marx
    This Month
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Correspondence

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Research Highlights

  • Somatic cells in the mouse can be converted to a pluripotent state merely through exposure to a physical stimulus.

    • Natalie de Souza
    Research Highlights
  • At last, a method to measure long-range vibrations in proteins may provide clues to the functional relevance of these motions.

    • Allison Doerr
    Research Highlights
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Methods in Brief

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Tools in Brief

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Research Highlights

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Commentary

  • Single-molecule super-resolution techniques emerged only several years ago but have revolutionized fluorescence microscopy of cellular structures. We discuss some key principles of these techniques, point out pitfalls, highlight recent developments and identify opportunities for the future.

    • Ulrike Endesfelder
    • Mike Heilemann
    Commentary
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Technology Feature

  • Careful strategizing helps make PCR sensitive enough for the most challenging experiments.

    • Vivien Marx
    Technology Feature
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News & Views

  • A first community experiment comparing the performance of analysis methods for single-particle tracking data declares no winner but reveals valuable information for users and developers.

    • Michael J Saxton
    News & Views
  • An approach is described that simplifies the isolation of rare human pluripotent stem cells engineered to carry precise disease-relevant mutations.

    • Ryan Forster
    • Dirk Hockemeyer
    News & Views
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Review Article

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Analysis

  • The first community competition designed to objectively compare the performance of particle tracking algorithms provides valuable practical information for both users and developers.

    • Nicolas Chenouard
    • Ihor Smal
    • Erik Meijering
    Analysis Open Access
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Brief Communication

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Article

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Addendum

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Erratum

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Corrigendum

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Erratum

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Search

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