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| Editorial | Top |
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The challenges of responsible methods p93
doi:10.1038/nmeth1104-93
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(32K)
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| Research Highlights | Top |
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Leave it to cleaver p95
Michael Eisenstein
doi:10.1038/nmeth1104-95
Abstract | Full text | PDF
(65K)
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Highlighting protein movement in living cells pp96 - 97
Daniel Evanko
doi:10.1038/nmeth1104-96a
Abstract | Full text | PDF
(131K)
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Don't mind the gap pp96 - 97
Michael Eisenstein
doi:10.1038/nmeth1104-96b
Abstract | Full text | PDF
(131K)
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News in Brief p97
doi:10.1038/nmeth1104-97
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(31K)
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Antibody 'sandwich' serves up phosphorylation data pp98 - 99
Michael Eisenstein
doi:10.1038/nmeth1104-98
Abstract | Full text | PDF
(60K)
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Know your colors pp100 - 101
Nicole Rusk
doi:10.1038/nmeth1104-100
Abstract | Full text | PDF
(76K)
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Fluorescent virus lets researchers in on the Gag p101
Michael Eisenstein
doi:10.1038/nmeth1104-101
Abstract | Full text | PDF
(26K)
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A golden opportunity for DNA detection p102
Daniel Evanko
doi:10.1038/nmeth1104-102a
Abstract | Full text | PDF
(30K)
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Proteins at the cross roads p102
Nicole Rusk
doi:10.1038/nmeth1104-102b
Abstract | Full text | PDF
(30K)
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| News and Views | Top |
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5,000 RNAi experiments on a chip pp103 - 104
Ben Lehner
& Andrew G Fraser
doi:10.1038/nmeth1104-103
Abstract | Full text | PDF
(76K)
See also: Article by Wheeler et al. |
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SNPs made routine pp104 - 105
Karl W Broman
& Eleanor Feingold
doi:10.1038/nmeth1104-104
Abstract | Full text | PDF
(70K)
See also: Article by Murray et al. | Brief Communication by Matsuzaki et al. |
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The age of high-throughput microRNA profiling pp106 - 107
Aurora Esquela-Kerscher
& Frank J Slack
doi:10.1038/nmeth1104-106
Abstract | Full text | PDF
(49K)
See also: Article by Nelson et al. |
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| Brief Communication | Top |
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Genotyping over 100,000 SNPs on a pair of oligonucleotide arrays pp109 - 111
Hajime Matsuzaki, Shoulian Dong, Halina Loi, Xiaojun Di, Guoying Liu, Earl Hubbell, Jane Law, Tam Berntsen, Monica Chadha, Henry Hui, Geoffrey Yang, Giulia C Kennedy, Teresa A Webster, Simon Cawley, P Sean Walsh, Keith W Jones, Stephen P A Fodor
& Rui Mei
Published online: 21 October 2004 | doi:10.1038/nmeth718
Abstract | Full text | PDF
(127K)
| Supplementary Information
See also: News and Views by Broman & Feingold |
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| Articles | Top |
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A highly informative SNP linkage panel for human genetic studies pp113 - 117
Sarah Shaw Murray, Arnold Oliphant, Richard Shen, Celeste McBride, Rhoberta J Steeke, Stuart G Shannon, Todd Rubano, Bahram G Kermani, Jian-Bing Fan, Mark S Chee
& Mark S T Hansen
Published online: 21 October 2004 | doi:10.1038/nmeth712
Abstract | Full text | PDF
(157K)
| Supplementary Information
See also: News and Views by Broman & Feingold |
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Identifying and quantifying in vivo methylation sites by heavy methyl SILAC pp119 - 126
Shao-En Ong, Gerhard Mittler
& Matthias Mann
Published online: 21 October 2004 | doi:10.1038/nmeth715
Abstract | Full text | PDF
(259K)
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RNAi living-cell microarrays for loss-of-function screens in Drosophila melanogaster cells pp127 - 132
Douglas B Wheeler, Steve N Bailey, David A Guertin, Anne E Carpenter, Caitlin O Higgins
& David M Sabatini
Published online: 21 October 2004 | doi:10.1038/nmeth711
Abstract | Full text | PDF
(610K)
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See also: News and Views by Lehner & Fraser |
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Simultaneous, coincident optical trapping and single-molecule fluorescence pp133 - 139
Matthew J Lang, Polly M Fordyce, Anita M Engh, Keir C Neuman
& Steven M Block
Published online: 21 October 2004 | doi:10.1038/nmeth714
Abstract | Full text | PDF
(546K)
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LigAmp for sensitive detection of single-nucleotide differences pp141 - 147
Chanjuan Shi, Susan H Eshleman, Dana Jones, Noriyoshi Fukushima, Li Hua, Antony R Parker, Charles J Yeo, Ralph H Hruban, Michael G Goggins
& James R Eshleman
Published online: 21 October 2004 | doi:10.1038/nmeth713
Abstract | Full text | PDF
(562K)
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Cell-free protein production and labeling protocol for NMR-based structural proteomics pp149 - 153
Dmitriy A Vinarov, Betsy L Lytle, Francis C Peterson, Ejan M Tyler, Brian F Volkman
& John L Markley
Published online: 21 October 2004 | doi:10.1038/nmeth716
Abstract | Full text | PDF
(380K)
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Microarray-based, high-throughput gene expression profiling of microRNAs pp155 - 161
Peter T Nelson, Don A Baldwin, L Marie Scearce, J Carl Oberholtzer, John W Tobias
& Zissimos Mourelatos
Published online: 21 October 2004 | doi:10.1038/nmeth717
Abstract | Full text | PDF
(309K)
| Supplementary Information
See also: News and Views by Esquela-Kerscher & Slack |
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| Protocol | Top |
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Cloning of short hairpin RNAs for gene knockdown in mammalian cells pp163 - 167
Patrick J Paddison, Michele Cleary, Jose Maria Silva, Kenneth Chang, Nihar Sheth, Ravi Sachidanandam
& Gregory J Hannon
doi:10.1038/nmeth1104-163
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(159K)
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| Technology Feature | Top |
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Bioinformatics—from genes to pathways pp169 - 176
Laura Bonetta
doi:10.1038/nmeth1104-169
Abstract | Full text | PDF
(604K)
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| Application Notes | Top |
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Identification of DNA binding proteins using the NoShift Transcription Factor Assay Kit pp177 - 179
Faye Bruggink
& Scott Hayes
doi:10.1038/nmeth1104-177
Abstract | Full text | PDF
(305K)
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| Classic Protocols | Top |
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A look back: Changes for the better p180
Michael Eisenstein
doi:10.1038/nmeth1104-180
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(28K)
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Rapid and efficient site-directed mutagenesis by the single-tube megaprimer PCR method pp181 - 182
doi:10.1038/nmeth1104-181
Abstract | Full text | PDF
(30K)
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