The following articles have appeared in Nature Methods after the original publication of the Focus issue and discuss additional important aspects of RNAi experiments, in mammalian cells as well as in other model organisms.
The Commentary (Echeverri et al.) invites an open public debate to define standards that would ensure the quality of datasets generated by large-scale RNAi screens and in particular to limit the risk of reporting false positives.
Please visit methagora, Nature Methods' commenting forum, to add your voice to the discussion.
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