News & Comment

  • News & Views |

    Crystallized anti-inflammatory drugs have been shown to inhibit fibrosis on the surface of a number of devices over a long-term period following implantation in rodents and non-human primates.

    • Ruud A. Bank
  • Editorial |

    We are launching a new column to talk about science with our readers from a broader perspective. Our first topic is mental health in academia.

  • News & Views |

    With their ability to give rise to many different cell types, stem cells have long been a target of scientists who seek to achieve control over their differentiation. New evidence suggests that stem cells influence their own fates through protein deposition and physical remodelling of their microenvironment.

    • Eric L. Qiao
    • , Sanjay Kumar
    •  & David V. Schaffer
  • News & Views |

    Violating the Aufbau principle is shown to be a successful strategy to improve the stability of neutral organic radicals used in organic light-emitting diodes.

    • Sebastian Reineke
  • News & Views |

    Thousands of electron diffraction patterns, collected stepwise by scanning transmission electron microscopy, are synchronized and mined to provide unprecedented maps of the nanostructure of ordered domains in organic electronics films.

    • Gitti L. Frey
    •  & Yaron Kauffmann
  • News & Views |

    Granular aluminium — a superconductor with high kinetic inductance — has been used to create a superinductor for a fluxonium superconducting qubit.

    • Joel I-Jan Wang
    •  & William D. Oliver
  • News & Views |

    A chemically and thermally stable metal–organic framework achieves exceptional separation of styrene from a complex mixture containing larger (ethylbenzene) and smaller (toluene and benzene) molecules.

    • Simon M. Vornholt
    •  & Russell E. Morris
  • News & Views |

    Two-dimensional cobalt oxide and cobalt nickel oxide sheets, with thicknesses around one nanometre, can form spontaneously from the transformation of three-dimensional nanocrystals in a solution-phase synthesis.

    • Kristen Fichthorn
  • News & Views |

    Highly stable and active Pt–Sn sub-nanometre clusters are located in sinusoidal zeolite channels, leading to improved and more stable propane dehydrogenation catalysts.

    • Bert M. Weckhuysen
  • Comment |

    3D printing is now widely used in aerospace, healthcare, energy, automotive and other industries. Metal printing, in particular, is the fastest growing sector, yet its development presents scientific, technological and economic challenges that must be understood and addressed.

    • T. DebRoy
    • , T. Mukherjee
    • , J. O. Milewski
    • , J. W. Elmer
    • , B. Ribic
    • , J. J. Blecher
    •  & W. Zhang
  • News & Views |

    The chiral magnetic exchange interaction, or Dzyaloshinskii–Moriya interaction, is found to propagate through dozens of atomic layers and also to be present in inhomogeneous amorphous alloys. These discoveries extend the parameter space available for realizing magnetic structures with chiral character.

    • Bartel Van Waeyenberge
  • News & Views |

    Measuring the 1s–2p splitting of direct and indirect excitons in van der Waals heterostructures allows their binding energy and dynamics to be determined.

    • Steven T. Cundiff
  • News & Views |

    An intermediate affinity state of integrin αIIBβ3 has been identified to be a key player in platelet mechanosignalling.

    • X. Frank Zhang
    •  & Xuanhong Cheng
  • News & Views |

    Controlled Pt loading on TiO2 nanoparticles enables single-site catalysts. With this, the coordination environment and catalytic activity can be obtained, allowing extraction of structure-function information.

    • E. Charles H. Sykes
  • Editorial |

    Synergy between materials and methods is helping to address open questions in magnetism and superconductivity.

  • News & Views |

    A comprehensive chemical space of potential inorganic ternary metal nitrides has been explored by computational methods as a guideline for their experimental synthesis and discovery.

    • Ralf Riedel
    •  & Zhaoju Yu
  • News & Views |

    Quantitative atomic-scale images of electric potentials at surfaces have now been obtained with a non-contact atomic force microscope by functionalizing the tip as a quantum dot sensor.

    • Mats Persson
  • Editorial |

    2D materials face challenges along the road to commercialization, with increasing efforts being made in order to satisfy industrial needs.

  • Comment |

    Electronic and photonic devices based on graphene have unique properties, leading to outstanding performance figures of merit. Mastering the integration of this unconventional material into an established semiconductor fabrication line represents a critical step towards commercialization.

    • Daniel Neumaier
    • , Stephan Pindl
    •  & Max C. Lemme
  • Comment |

    The past few years have witnessed significant development in graphene research, yet a number of challenges remain for its commercialization and industrialization. This Comment discusses relevant issues for industrial-scale graphene synthesis, one of the critical aspects for the future graphene industry.

    • Li Lin
    • , Hailin Peng
    •  & Zhongfan Liu
  • News & Views |

    The polarity of charge carriers — positive or negative — is found to depend on the direction from which you look.

    • Brian Skinner
    •  & Justin C. W. Song
  • News & Views |

    Over-expression of a transcriptional factor, Alx3, has been shown to revitalize the regenerative capacity of adult progenitor cells to promote enhanced stromal vascularization and formation of parenchymal dental pulp tissue in vivo.

    • Sarah E. Millar
  • News & Views |

    An oxygen-free method of growing transition metal selenides leads to atomically thin films with unprecedented robustness against the most hostile conditions.

    • Miguel M. Ugeda
  • News & Views |

    By chemically treating wood it is possible to fabricate a nanofluidic device for generating electricity from the harvesting of ubiquitous low-grade heat.

    • Rama Venkatasubramanian
  • News & Views |

    A tender X-ray momentum-resolved spectroscopy for probing elementary excitations in 4d quantum materials is reported and used to measure dispersive spin excitations in a ruthenate microcrystal.

    • Wei-Sheng Lee
    •  & Brian Moritz
  • News & Views |

    A magnetic-field-dependent spectroscopy study on single perovskite nanocrystals reveals the spectral signatures of an exciton dark state below the bright triplet states.

    • Andries Meijerink
    •  & Freddy T. Rabouw
  • Comment |

    Oxides of non-magnetic cations exhibit elusive signs of weak temperature-independent ferromagnetism. The effect is associated with surface defects, but it defies conventional explanation. Possible hypotheses are a spin-split defect impurity band, or giant orbital paramagnetism related to zero-point vacuum fluctuations.

    • J. M. D. Coey
  • News & Views |

    Using electric field gating, researchers demonstrate switching from a single- to a multi-condensate superconducting state at an oxide-based interface, and show that this transition leads to an overall weakening of the superconductivity.

    • H. Hilgenkamp
    •  & A. E. M. Smink
  • News & Views |

    Coherent shaping of matter waves in temporal and spatial domains by photon-induced near fields opens up new possibilities for the quantum control of matter.

    • Jun Yuan
  • Comment |

    Highly quantitative, robust, single-cell analyses can help to unravel disease heterogeneity and lead to clinical insights, particularly for complex and chronic diseases. Advances in computer vision and machine learning can empower label-free cell-based diagnostics to capture subtle disease states.

    • Minh Doan
    •  & Anne E. Carpenter
  • Editorial |

    Machine learning is swiftly infiltrating many areas within the healthcare industry, from diagnosis and prognosis to drug development and epidemiology, with significant potential to transform the medical landscape.

  • Comment |

    At the recent Artificial Intelligence Applications in Biopharma Summit in Boston, USA, a panel of scientists from industry who work at the interface of machine learning and pharma discussed the diverging opinions on the past, present and future role of AI for ADME/Tox in drug discovery and development.

    • Barun Bhhatarai
    • , W. Patrick Walters
    • , Cornelis E. C. A. Hop
    • , Guido Lanza
    •  & Sean Ekins
  • News & Views |

    By measuring the photocurrent from illuminated Weyl semimetals, an optical signature of topological properties arising from Weyl fermions has been revealed, highlighting nonlinear optical effects and applications of Weyl semimetals.

    • Hongming Weng
  • Comment |

    Rapid progress in machine learning is enabling opportunities for improved clinical decision support. Importantly, however, developing, validating and implementing machine learning models for healthcare entail some particular considerations to increase the chances of eventually improving patient care.

    • Po-Hsuan Cameron Chen
    • , Yun Liu
    •  & Lily Peng
  • News & Views |

    Organic donor–acceptor heterojunctions can show efficient electroluminescence and at the same time generate charges under photovoltaic operation.

    • Wolfgang Brütting
  • News & Views |

    Potassium–air batteries, which suffer from oxygen cathode and potassium metal anode degradation, can be cycled thousands of times when an organic anode replaces the metal.

    • Yann K. Petit
    •  & Stefan A. Freunberger
  • News & Views |

    Impulsive Raman spectroscopy reveals how atoms are pushed into action by light absorption. The surprising sensitivity of this behaviour to the polaronic character of 2D perovskites opens up new avenues for tailored light–matter interactions.

    • Christoph Schnedermann
    • , Akshay Rao
    •  & Philipp Kukura
  • News & Views |

    A two-step method has been developed for the accelerated and efficient generation of human kidney organoids using in vitro and in ovo culture in a three-dimensional environment.

    • Susana M. Chuva de Sousa Lopes
  • News & Views |

    Strong spin–electric coupling related to modulation of magnetic coupling has now been observed in polar spin chains. This is a first step towards switching quantum bit interactions by localized electric fields.

    • Joris van Slageren
  • Editorial |

    The redefinition of SI units removes materiality from science’s weights and measures. There’s logic to the decision, but it reminds us what we still don’t know about nature’s scales.

  • News & Views |

    Irradiating a PbTiO3/SrTiO3 superlattice with ultrafast UV light pulses modifies elastic and electrostatic interactions, resulting in the formation of a stable complex 3D supercrystal.

    • J. M. Gregg
  • News & Views |

    Neural probes that mimic the subcellular structural features and mechanical properties of neurons assimilate across several structures of the brain to provide chronically stable neural recordings in a mouse model.

    • Jeffrey R. Capadona
    • , Andrew J. Shoffstall
    •  & Joseph J. Pancrazio