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Regenerative medicine

Noodle gels for cells

Heating and cooling of peptide amphiphile suspensions converts disorganized nanofibres into liquid-crystalline nanofibre bundles that gel on addition of salts. The noodle-shaped strings of gel can entrap and align cells.

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Figure 1: A schematic of cell growth on synthetic engineered scaffolds made by different routes.
Figure 2: A schematic of the thermal process to form liquid-crystalline nanofibre bundles.

References

  1. http://en.wikipedia.org/wiki/La_mian

  2. Larson, R. The Structure and Rheology of Complex Fluids (Topics in Chemical Engineering, Oxford Univ. Press, 1999).

    Google Scholar 

  3. Zhang, S. et al. Nature Mater. 9, 594–601 (2010).

    Article  CAS  Google Scholar 

  4. Engel, E. et al. Trends Biotechnol. 26, 39–47 (2007).

    Article  Google Scholar 

  5. Merzlyak, A., Indrakanti, S. & Lee, S. W. Nano Lett. 9, 846–852 (2009).

    Article  CAS  Google Scholar 

  6. Hartgerink, J. D., Beniash, E. & Stupp, S. I. Proc. Natl Acad. Sci. USA 99, 5133–5138 (2002).

    Article  CAS  Google Scholar 

  7. Lutolf, M. P. & Hubbell, J. A. Nature Biotechnol. 23, 47–55 (2005).

    Article  CAS  Google Scholar 

  8. de las Heras Alarcón, C., Pennadam, S. & Alexander, C. Chem. Soc. Rev. 34, 276–285 (2005).

    Article  Google Scholar 

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Deming, T. Noodle gels for cells. Nature Mater 9, 535–536 (2010). https://doi.org/10.1038/nmat2789

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