Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Nanomedicine

Veni, vidi, vici and then... vanished

Non-toxicity in multifunctional inorganic nanoparticles is rare. However, with careful engineering of silicon-based nanoparticles they can be used in vivo as imaging and drug-delivery agents and later degraded and cleared without toxic effects.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Nanoparticle structure and accumulation in mouse tumours.

References

  1. Rotello, V. M. Adv. Drug Del. Rev. 60, 1225 (2008).

    Article  CAS  Google Scholar 

  2. Forrest, M. L. & Kwon, G. S. Adv. Drug Del. Rev. 60, 861–862 (2008).

    Article  CAS  Google Scholar 

  3. Park, J.-H., Gu, L., von Maltzahn, G., Ruoslahti, E., Bhatia, S. N. & Sailor, M. J. Nature Mater. 8, 331–336 (2009).

    Article  CAS  Google Scholar 

  4. Heinrich, J. L., Curtis, C. L., Credo, G. M., Sailor, M. J. & Kavanagh, K. L. Science 255, 66–68 (1992).

    CAS  Google Scholar 

  5. Godefroo, S. et al. Nature Nanotech. 3, 174–178 (2008).

    Article  CAS  Google Scholar 

  6. Trewyn, B. G., Slowing, I. I., Giri, S., Chen, H. T & Lin, V. S.-Y. Acc. Chem. Res. 40, 846–853 (2007).

    Article  CAS  Google Scholar 

  7. Popplewell, J. F. et al. J. Inorg. Biochem. 69, 177–180 (1998).

    Article  CAS  Google Scholar 

  8. Schubert, U. S. & Wouters, D. Angew. Chem. Int. Ed. 43, 2480–2495 (2004).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lin, VY. Veni, vidi, vici and then... vanished. Nature Mater 8, 252–253 (2009). https://doi.org/10.1038/nmat2413

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmat2413

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing